Unleashing Fibrotic Secrets: Coupling the Power of Laser Microdissection with Mass Spec

Identify potentially thousands of proteins in lesions extracted from heterogeneous tissue samples and explore their function in diseases by combining laser microdissection and mass spectrometry. 

In this webinar, you will learn:

• How to overcome problems associated with studying heterogeneous tissues by combining laser microdissection with mass spectrometry;
• Ways to explore the protein composition and molecular function of proteins in pathological tissue lesions;
• About the technical capabilities of LCM-MS using lung fibrosis as an example.

Tissue heterogeneity is a significant challenge when analyzing proteins in tissue samples to identify disease states. 

See how combining laser microdissection with mass spectrometry (LCM-MS) on fixed and stained tissues lets you explore the protein networks within pathological features to shed light on their molecular functions.

Using hallmark lesions of lung fibrosis in the honeycomb airways and fibroblastic foci as an example, we will showcase how this technology can detect over 4,900 proteins from tissue volumes as low as 0.005 mm3.