Impact of CMV Infection on the T-cell Repertoire
On-demand
Dr. Nate Polaske
Dr. Nate Polaske is an organic chemist with 15 years of research and development experience in cancer diagnostics and therapeutics. At Adaptive, he works closely with academic customers, providing technical support and training across Adaptive's research product portfolio.
CloseDr. Paul Fields
Dr. Paul Fields is a computational biologist with more than 10 years of research experience and is an expert in the field of immunosequencing. He currently leads a team at Adaptive that works with academic and biopharmaceutical partners to perform data analysis and integrate immunoSEQ Data to address broader biological questions.
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In this webinar, you will discover:
- How the immunoSEQ® Assay has been used to gain mechanistic insights into the effects of CMV infection on T cells;
- Insights into the age-related impact of CMV infection on the T-cell repertoire, effect of CMV status of donors in bone marrow and stem cell transplants, and identifying T-cell related signature of CMV exposure;
- More about a CMV classifier developed by Adaptive Biotechnologies to better understand and identify CMV infection, and its utility in a research setting.
Cytomegalovirus (CMV) is globally widespread; up to 50-100% of people have been infected with CMV. While infection is usually asymptomatic, CMV has been shown to have significant impacts on a person’s T-cell repertoire, which may impact their susceptibility to other infections and responsiveness to vaccines and immunotherapies.
In this webinar, Dr. Paul Fields and Dr. Nate Polaske discuss how the immunoSEQ® Assay has been used to gain mechanistic insights into the effects of CMV infection on T cells, and highlight a T-cell repertoire-based classifier, developed by Adaptive Biotechnologies to identify CMV status with high sensitivity and specificity, which has research utility across a range of therapeutic areas.
For Research Use Only. Not for use in diagnostic procedures.
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