How the immune response in severe COVID-19 patients was assessed.
The change in the T-cell population for patients suffering from severe COVID-19.
Changes in expression of genes related to T-cell activation and differentiation.
How this information may help researchers understand the immune response to COVID-19 and inform treatment strategies.
The global patient mortality rate of COVID-19 has been 3-4% of confirmed cases since the outbreak first began. The response of the immune system may play a critical role in the disease progression, severity, and mortality of COVID-19, with some studies showing decreased T cells and natural killer cells in patients infected with SARS-CoV-2, the virus responsible for COVID-19.

Professor Dexi Chen, the Director of the Beijing Institute of Hepatology, investigated the immune system of patients suffering from severe COVID-19. The study uncovered a decreased proportion of T-cells and downregulation of genes related to T-cell activation and differentiation in severe COVID-19 patients.

This information may help researchers understand the immune response to COVID-19 and inform treatment strategies for the disease.

For Research Use Only. Not For Use In Diagnostic Procedures.

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