Analyte Binding Following Sample Filtration in HPLC
On-demand


Vivek Joshi
Vivek Joshi, PhD is an Applications and Market Adoption Senior Manager at MilliporeSigma. He develops new products and applications for products that span analytical workflows, molecular and protein science workflows, and cell culture workflows. He recently presented a sample preparation module in the Drug Dissolution Training offered by the United States Pharmacopeia (USP).
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In this webinar you will learn:
- How membrane properties impact analyte binding.
- Which physico-chemical properties of analytes impact analyte binding.
- The effect of analyte concentration on binding.
- Strategies to minimize analyte binding to syringe filters.
High-pressure liquid chromatography (HPLC) analysis is very commonly used in various industries for quantitation of analytes. However, such quantitation can be affected by analyte binding to syringe filters. Binding can be caused by factors including analyte concentration, and the physico-chemical properties of the analyte and membrane. Although sample preparation is an essential step, any loss of analyte to sample preparation can be detrimental to quantitation.
Join us in our latest webinar as we discuss some factors that have an influence on analyte binding and strategies to minimize analyte binding to syringe filters.
The life science business of Merck KGaA, Darmstadt, Germany operates as MilliporeSigma in the U.S. and Canada.
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